The Isambert LabComputational BiologyCNRS, Institut Curie and Prairie Institute, Paris April 2026: New PhD position opening with Prairie - Paris School of AI on Causal discovery and Information Theory for high-dimensional biological data!... April 2026: New paper on human haemapoietic stem cell differentiation to appear in Nature Comm in collaboration with the Perie lab, congrats Tiziana !... April 2026: New paper on a cellular therapy against multiple sclerosis in mice to appear in Immunity in collaboration with the Fillatreau lab, congrats Louise !... Feb 2026: New meeting report on cross-disciplinary methodologies for whole-person research to appear in npj Imaging, congrats Irene and Thomas !... Jan 2026: New paper on tumor immune infiltration to appear in Science Immunology in collaboration with Helene Moreau, Lennon lab (U932), congrats Franck !... 16 Dec 2025: Congrats Nikita for your PhD defense !... 5 Dec 2025: Congrats Orianne for your PhD defense !... Nov 2025: 6th international course on "Multiscale Integration in Biological Systems", Institut Curie, Paris, Nov 12-18, 2025... Sept 2025: New paper on the identification of novel JAK1 variants associated with immune dysregulation in collaboration with Rieux-Laucat lab, Imagine Institute, congrats Orianne !... July 2025: Nikita and Herve present their paper at ICML 2025 conference !... June 2025: New paper on prediction of chemotherapy on tumor spheroids to appear in Small Science in collaboration with C Wilhelm and JL Viovy, congrats Tiziana and Franck !... May 2025: New paper on a search-and-score algorithm for ancestral graphs accepted at ICML 2025 conference, congrats Nikita !... April 2025: New paper on cell-cell communication causalCCC to appear in Nucleic Acids Res, congrats Louise and Orianne !... Apr 2025: Welcome to Hugo (Masters student) !... Mar 2025: Congrats Louise for your new position at the Brain Institute, Paris !... Feb 2025: Our new cell-cell communication server causalCCC is online, congrats Louise and Orianne !... Feb 2025: Welcome to Alexander (Engineer) !... Jan 2025: New paper on bioRxiv in collaboration with the Lennon-Dumenil lab, Institut Curie, congrats Franck !... Jan 2025: New paper on synthetic health data generation published in npj Digital Medicine in collaboration with Institut Roche !... Dec 2024: New paper on 'MIIC_search&score' published on arXiv !... Dec 2024: Congrats Louise for your PhD defense !... Nov 2024: Welcome to Ali and Ouahab (PhD students)!... Sept 2024: New MIIC 2.0.3 version available at CRAN, congrats Franck !... Sept 2024: New press release for our 'CausalXtract' paper published at eLife !... April 2024: Several PhD and Postdoc position openings on single cell multi-omics data analysis!... March 2024: New article published in Development in collaboration with the Jaffredo lab, Sorbone University !... March 2024: Welcome Holly, visiting PhD student from Imperial College London (Bravi lab) !... Feb 2024: New paper accepted (in principle) at iScience !... Jan 2024: New AI4scMED project starts in collaboration with the Cantini lab at Pasteur !... Dec 2023: Congrats Franck for your PhD defense!... Nov 2023: 5th international course on "Multiscale Integration in Biological Systems", Institut Curie, Paris, Nov 8-14, 2023... Oct 2023: New grant awarded by the FRM (Fondation pour la Recherche Medicale) in collaboration with S Fillatreau (PI)!... Sept 2023: Lab Retreat at the CIRM, Luminy, Marseille!... Sept 2023: Welcome to Louis (PhD student)!... June 2023: Launch of the ARTiDe European project on Autoantigen-specific adoptive regulatory T cell therapy against type 1 diabetes (PI S Fillatreau, Institut Necker)!... April 2023: NEW PhD position opening on Causal inference methods for heterogeneous biological data (funding MecaCell3D consortium project)!... March 2023: Paper on Reliable and scalable causal network discovery on arXiv!... February 2023: Welcome to Aymeric (M2 student) to work on NOWAC database!... January 2023: Paper on Metabolically primed multipotent hematopoietic progenitors on bioRxiv, collaboration with the Perie lab, congrats Jason!... November 2022: Welcome to Orianne (PharmD-PhD student), collaboration with the Rieux-Laucat lab, Institut Imagine!... October 2022: Welcome to Tiziana (PhD student) and Nikita (PhD student)!... August 2022: New paper on interactive exploration of breast cancer clinical network published in npj Digital Medicine!... July 2022: Congrats Marcel for your PhD defense!... June 2022: Congrats Honghao for your new position at 0wkin!... April 2022: Filled! New PhD position opening awarded by CNRS and Imperial College London on Causal discovery for Imaging and multi-omics data!... February 2022: Congrats Vincent for your new position at 0wkin!... January 2022: Filled! EU Cofund PhD position opening... December 15, 2021: Congrats Vincent and Honghao for your PhD defenses!... November 2021: New paper on reliable causal discovery accepted at why21 @ NeurIPS 2021!... November 2021: 4th international course on "Multiscale Integration in Biological Systems", Institut Curie, Paris, Nov 4-10, 2021 (see videos of first three editions)... October 2021: Welcome to Louise (PhD student) and Liza (MD-PhD postdoc)!... June 2021: New paper on Septin-membrane interactions with Aurelie Bertin and Pierre-Emmanuel Milhiet to appear in Nanoscale... May 2021: New paper on Transfer Entropy in image analysis with the Martinelli lab to appear in Patterns... April 2021: Welcome to Adrien (trainee) in the lab... March 2021: New Postdoc opening on clinical network reconstructions including DL image analysis, contact us... Oct 2020: MIIC released on CRAN, congrats Vincent and Honghao !... Sept 2020: Welcome to Franck (engineer) and Leonardo (visiting PhD student) in the lab... Aug 2020: MIIC R package just released !... July 2020: New research grant awarded by ITMO Cancer (PI: H Isambert, co-PIs: F Reyal and T Walter): Postdoc and Engineer positions available!... July 2020: Vincent awarded a fourth year of PhD fellowship from ARC Foundation!... May 2020: Our paper on Inferring gene networks in bone marrow Hematopoietic Stem Cell-supporting stromal niches populations (coll P Charbord, Sorbonne University, Paris) to appear in iScience... April 2020: Our paper on clinical networks in neurodegenerative diseases (Coll M Verny, La Pitie-Salpetrieres Hospital,Paris) to appear in PLoS Comput Biol... January 2020: Our experimental paper on ohnolog susceptibility to gain-of-function mutations to appear in Channels!... November 2019: Welcome to Maria from the Martinelli lab, University of Roma... October 2019: Our NAR paper on the "Ohnologs" database recommended by F1000Prime... September 2019: NeurIPS 2019! Our paper on interpretable constraint-based causal structure learning to appear in NeurIPS 2019... July 2019: Our Database "Ohnologs" has been expanded to include 27 vertebrates... June 2019: Congratulation Nadir for your PhD defense! January 2019: our paper on curvature sensitive septin-membrane interaction just published in Nature Communications (collaboration with the Levy and Bassereau groups, UMR168)... Contact us for Postdoc, PhD and Masters projects in Machine Learning, AI and computational biology...